Bibliography
No two drugs will require the same solution
Our leadership in the field of adherence research is objectively demonstrated by the bibliography of over 518 peer-reviewed papers published by researchers who have used MEMS monitors in their work since the first peer-reviewed paper appeared in 1989. It is an unparalleled record of product use, in which each group of authors report their findings and experiences in using MEMS monitors to compile and analyze drug dosing histories in ambulatory patients. During the past 23 years, research questions and methods of data analysis have gained in sophistication, as successive generations of MEMS monitors have gained in memory size, reliability in data-capture and storage, and increasing independence from environmental vicissitudes. Paralleling those technological advances have been advancement in the biostatistical analysis of dosing-history data, which involve not only quantities of drug taken, but the time-intervals between successive doses, and discovery of drug holidays, time-of-day, day-of-week, and other important facets of ambulatory patients’ drug dosing histories. Acquiring data at a default rate of 4 samples per hour (adjustable if desired), MEMS monitoring is the only method that has been able to detect important day-to-day differences in regimen execution, and the precise times of onset and cessation of dosing, by ambulatory patients in a wide variety of clinical settings.
Access online the searchable repository of peered reviewed publications on electonic compilation of drug dosing histories.
